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DCPrime is a Dutch biotech company which has developed a novel approach to cancer vaccines. The company’s unique platform technology consists of sustainable dendritic progenitor cells (DCOne™) and a proprietary method to expand these and to create functional mature dendritic cells (DC).

These cells, in some indications loaded with cancer antigens for targeted treatment, are used as standardized, off-the-shelf, therapeutic products that can stimulate the patient’s immune system in a specific manner. The platform combines the power of DC-based vaccines with the advantages of allogeneic stimulation of the immune system, and the simple logistics of off-the-shelf products.

DIGNA Biotech is a private biotechnology company headquartered in Pamplona (Spain), with offices in Madrid and Pennsylvania (USA). It was founded in 2004 as a spin-off of the University of Navarra. The firm currently has a pipeline of 9 products at different stages of development in 3 therapeutic areas: Inflammatory/Autoimmune, Cardiovascular and Liver diseases.

 Digna Biotech is seeking private funding to spin out a new biotech company to conduct Phase IIb and Phase III trials of its more advanced candidate, a cytokine inhibitor for the treatment of patients with Systemic Sclerosis and Localized Scleroderma. The product (Disitertide) has already completed Phase I, Phase IIa and open-label extension (OLE) clinical trials under a topical formulation in patients with systemic sclerosis. Orphan drug designation by both FDA and EMA has been granted in the two indications.