
Virometix AG
Virometix is a privately held young innovative Swiss Biotech company developing a new class of vaccines, which should overcome limitations of current biological vaccines in terms of safety, efficacy, speed, stability and manufacturing cost. Virometix Synthetic Virus-Like Nanoparticle (SVLP) technology platform offers the following value propositions:
Safety. Virometix SVLP-based vaccines avoid the use of life pathogens and the safety concerns associated with the biological manufacturing processes used for conventional vaccines.
Quality. SVLPs are based on a proprietary lipopeptide self-assembly process that leads to atomically defined nanoparticles with a constant size and number of lipopeptide monomers per particle, which increases the specificity and quality of the elicited immune response and assures lot-to-lot consistency.
Efficacy. SVLPs efficiently deliver antigens to antigen presenting cells for optimal B- and T-cell responses and induce antibodies that bind with very high affinity to the native target antigen.
Convenience. SVLPs do not require sonication, refolding, extrusion or similar processes. SVLPs can be prepared by simply dissolving freeze-dried lipopeptide monomers in a buffer suitable for injection shortly before use.
The protective potential of Virometix nanoparticles has been demonstrated for various targets in in vitro and in vivo. Virometix currently develops vaccines for infectious diseases and cancer and offers collaborative research and licensing partnerships for selected vaccines in these areas, and licensing opportunities for selected areas outside Virometix core focus.
Arin Ghasparian
CEO
XIBER Science GmbH
Xiber is a biopharmaceutical start–up company. Xiber develops new peptide drugs to improve outcome of critical care & transplant patients. Xiber’s peptide drugs preserve organ function & prevent organ failure. Xiber will enter market by two niche indications: Acute Lung Injury & Primary Graft Dysfunction after Lung Transplantation – with a total market volume of 630 Mio. USD.
In 2015 Xiber will complete the preclinical development for both indications. A phase I clinical trial will start in the beginning of 2016.
Xiber is a spin-off of the Medical University of Vienna. The majority of the shares is owned by the founders. The University holds a non-controlling interest and rewards its shares by providing cooperation, infrastructure, facility services and management support.
To drive its developmental program till the completion of a phase I trial Xiber needs ~ 4 Mio €. This is largely covered by Austrian funds and loans. For the remaining Xiber seeks 2 Mio € equity from VC partner. Xiber has already signed a LOI with an established VC company.